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Hashimoto’s Thyroiditis: Why Are Women Affected More Often?
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Hashimoto’s Thyroiditis: Why Are Women Affected More Often?

Hashimoto’s autoimmune thyroiditis is one of the most common thyroid disorders. Its hallmark is that the immune system mistakenly attacks the thyroid’s own tissues, causing chronic inflammation and gradually reducing hormone production. Women are about five times more likely to develop this condition than men. Why does this happen?

Dr. Oxana
Article author

Dr. Oxana

Endocrinologist

Blame It on Hormones

Female hormones, especially estrogens, enhance immune system activity. While this helps the body fight infections more effectively, it also raises the risk that the immune system will “go off course” and start attacking its own cells. In contrast, testosterone in men tends to have a calming effect on immune responses, lowering the likelihood of autoimmune diseases.

Passed Down Through Generations

Studies show that genes linked to autoimmune processes are more frequently activated in women. In addition,=== women have two X chromosomes, which carry many genes that influence immune function. This “double set” can lead to breakdowns in immune regulation.

A Full Reset

Pregnancy places a tremendous strain on a woman’s body, particularly the thyroid and the immune ...

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October 28, 2025
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Hashimoto’s Thyroiditis: Why Are Women Affected More Often? - Ornament Community